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2-dihydropyridin-3-yl)methyl]-2-methyl-1-[(1R)-1-(oxan-4-yl)ethyl]-1H-indole-3-carboxamide
It has improved PK properties relative to UNC0638 and displayed modest brain penetration in vivo
23-hexaoxo-5
which is an antihistamine
YAP-TEAD-IN-1 TFA 64 Racemate 2-dihydropyridin-3-yl)methyl]-2-methyl-1-[(1R)-1-(oxan-4-yl)ethyl]-1H-indole-3-carboxamideYAP TEAD IN 1 TFA is a potent and competitive peptide inhibitor of YAP TEAD interaction (IC50=25 nM). YAP TEAD IN 1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50 171) (Kd= 40 nM). Product information CAS Number: 1659305 79 9 Molecular Weight: 2133. 89 Formula: C95H145ClF3N23O23S2 Chemical Name: (4S) 4 ((2S) 1 ((2S) 1 ((2S) 2 ((3S, 6S, 9S, 18S, 21S, 24S, 27S, 30S, 35aS) 18 ((S) 2 ((S) 1 ((S) 2 acetamido